Sepetaprost-ONO-9054-生命科学试剂-MCE.pdfVIP

Hotline:400-820-3792

Inhibitors•ScreeningLibraries•Proteins

www.MedChemE

Sepetaprost

Cat.No.:HY-128538

CASNo.:1262873-06-2

Synonyms:ONO-9054

分⼦式:C₂₆H₃₆F₂O₆

分⼦量:482.56

作⽤靶点:ProstaglandinReceptor

作⽤通路:GPCR/GProtein

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Sepetaprost(ONO-9054)是前列腺素E3受体(prostaglandinE3receptor)和前列腺素F受体(prostaglandin

Freceptor)的双重激动剂。Sepetaprost能够降低眼内压，可⽤于⾼眼压症和开⾓型青光眼的研究[1]。

IC50TargetEP3FPReceptor

REFERENCES

[1].SutoF,etal.ANovelDualAgonistofEP3andFPReceptorsforOAGandOHT:Safety,Pharmacokinetics,andPharmacodynamicsof

ONO-9054inHealthyVolunteers.InvestOphthalmolVisSci.2015Dec;56(13):7963-70.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

Tel:400-820-3792;021Fax:021E-mail:tech@MedChemE

1/1