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Sigma-LIGAND-1(Standard)

Cat.No.:HY-101626R

CASNo.:139652-01-0

分⼦式:C₂₇H₃₃NO₄

分⼦量:435.56

作⽤靶点:SigmaReceptor;ReferenceStandards

作⽤通路:NeuronalSignaling;Others

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Sigma-LIGAND-1(Standard)是Sigma-LIGAND-1(HY-101626)的分析标准品。本产品⽤于研究及分析应⽤。

Sigma-LIGAND-1是⼀种选择性sigma受体配体，在DTG和PPP位点的IC50分别为16nM，19nM。Sigma-

LIGAND-1对多巴胺D2受体的Ki为4000nM。

IC50TargetIC50:16nM(DTGsiteofsigmareceptor),19nM(PPPsiteofsigmareceptor)[1]

Ki:4000nM(DopamineD2receptor)[1]

REFERENCES

[1].EricksonRH,etal.(Aminoalkoxy)chromones.Selectivesigmareceptorligands.JMedChem.1992May1;35(9):1526-35.

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