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Susalimod

Cat.No.:HY-100485

CASNo.:149556-49-0

分⼦式:C₂₁H₁₆N₂O₅S

分⼦量:408.43

作⽤靶点:DrugDerivative

作⽤通路:Others

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性Susalimod是⼀种免疫调节剂，是Sulfasalazine(HY-14655)的类似物。Susalimod可降低LPS诱导的⼩⿏⾎

清TNF-α⽔平[1][2]。

REFERENCES

[1].GozziP,etal.Pharmacokinetic-pharmacodynamicmodelingoftheimmunomodulatingagentsusalimodandexperimentallyinduced

tumornecrosisfactor-alphalevelsinthemouse.JPharmacolExpTher.1999Oct;291(1):199-203.

[2].Påhlman,etal.Extensivebiliaryexcretionofthesulfasalazineanalogue,susalimod,butdifferentconcentrationsinthebileductin

variousanimalspeciescorrelatingtospecies-specifichepatobiliarytoxicity.PharmacolToxicol.1999Sep;85(3):123-9.

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