tert-Butyl-1-hydroxymethyl-5-azaspiro-2-4-heptane-5-carboxylate-生命科学试剂-MCE.pdfVIP

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tert-Butyl1-(hydroxymethyl)-5-azaspiro[2.4]heptane-5-carboxylate

Cat.No.:HY-W056644

CASNo.:1330766-02-3

分⼦式:C₁₂H₂₁NO₃

分⼦量:227.3

作⽤靶点:PROTACLinkers

作⽤通路:PROTAC

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性tert-Butyl1-(hydroxymethyl)-5-azaspiro[2.4]heptane-5-carboxylate是⼀种PROTAClinker，可⽤于合成

PROTAC分⼦。

体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE906ubiquitinligase

andtheotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto

selectivelydegradetargetproteins.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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