tert-Butyl-6-iodohexanoate-生命科学试剂-MCE.pdfVIP

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tert-Butyl6-iodohexanoate

Cat.No.:HY-W460254

CASNo.:67899-04-1

分⼦式:C₁₀H₁₉IO₂

分⼦量:298.16

作⽤靶点:PROTACLinkers

作⽤通路:PROTAC

储存⽅式:4°C,protectfromlight

*Insolvent:-80°C,6months;-20°C,1month(protectfrom

light)

BIOLOGICALACTIVITY

⽣物活性tert-Butyl6-iodohexanoate是⼀种PROTAClinker，可⽤于合成PROTAC分⼦。

体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE1043ubiquitinligase

andtheotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto

selectivelydegradetargetproteins.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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