tert-Butyl-6-hydroxyspiro-3-3-heptan-2-yl-carbamate-生命科学试剂-MCE.pdfVIP

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tert-Butyl(6-hydroxyspiro[3.3]heptan-2-yl)carbamate

Cat.No.:HY-34928

CASNo.:1000933-99-2

分⼦式:C₁₂H₂₁NO₃

分⼦量:227.3

作⽤靶点:PROTACLinkers

作⽤通路:PROTAC

储存⽅式:Powder-20°C3years

4°C2years

Insolvent-80°C6months

-20°C1month

BIOLOGICALACTIVITY

⽣物活性tert-Butyl(6-hydroxyspiro[3.3]heptan-2-yl)carbamate是⼀种PROTAClinker，可⽤于合成PROTAC分⼦。

体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE880ubiquitinligase

andtheotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto

selectivelydegradetargetproteins.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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