tert-Butyl-6-formyl-2-azaspiro-3-3-heptane-2-carboxylate-生命科学试剂-MCE.pdfVIP

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tert-Butyl6-formyl-2-azaspiro[3.3]heptane-2-carboxylate

Cat.No.:HY-W056306

CASNo.:1440960-67-7

分⼦式:C₁₂H₁₉NO₃

分⼦量:225.29

作⽤靶点:PROTACLinkers

作⽤通路:PROTAC

储存⽅式:-20°C,storedundernitrogen

*Insolvent:-80°C,6months;-20°C,1month(storedunder

nitrogen)

BIOLOGICALACTIVITY

⽣物活性tert-Butyl6-formyl-2-azaspiro[3.3]heptane-2-carboxylate是⼀种PROTAClinker，可⽤于合成PROTAC分⼦

。

体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE1041ubiquitinligase

andtheotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto

selectivelydegradetargetproteins.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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