tert-Butyl-6-hydroxymethyl-2-azaspiro-3-3-heptane-2-carboxylate-生命科学试剂-MCE.pdfVIP

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tert-Butyl6-(hydroxymethyl)-2-azaspiro[3.3]heptane-2-carboxylate

Cat.No.:HY-W056318

CASNo.:1363381-93-4

分⼦式:C₁₂H₂₁NO₃

分⼦量:227.3

作⽤靶点:PROTACLinkers

作⽤通路:PROTAC

储存⽅式:Storeatroomtemperature3years

*Insolvent:-80°C,6months;-20°C,1month(Storeatroom

temperature3years)

BIOLOGICALACTIVITY

⽣物活性tert-Butyl6-(hydroxymethyl)-2-azaspiro[3.3]heptane-2-carboxylate是⼀种PROTAClinker，可⽤于合成

PROTAC分⼦。

体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE1036ubiquitinligase

andtheotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto

selectivelydegradetargetproteins.

McePdfHeight

Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

Forresearchuseonly.

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