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- 2026-02-27 发布于上海
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Hotline:400-820-3792
Inhibitors•ScreeningLibraries•Proteins
www.MedChemE
tert-Butyl6-hydroxy-2-azaspiro[3.4]octane-2-carboxylate
Cat.No.:HY-W050186
CASNo.:1363381-95-6
分⼦式:C₁₂H₂₁NO₃
分⼦量:227.3
作⽤靶点:PROTACLinkers
作⽤通路:PROTAC
储存⽅式:Storeatroomtemperature3years
*Insolvent:-80°C,6months;-20°C,1month(Storeatroom
temperature3years)
BIOLOGICALACTIVITY
⽣物活性tert-Butyl6-hydroxy-2-azaspiro[3.4]octane-2-carboxylate是⼀种PROTAClinker，可⽤于合成PROTAC分⼦
。
体外研究PROTACscontaintwodifferentligandsconnectedbyalinker;oneisaligandforanE1042ubiquitinligase
andtheotherisforthetargetprotein.PROTACsexploittheintracellularubiquitin-proteasomesystemto
selectivelydegradetargetproteins.
McePdfHeight
Caution:Producthasnotbeenfullyvalidatedformedicalapplications.
Forresearchuseonly.
Tel:400-820-3792;021Fax:021E-mail:tech@MedChemE
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