肠道菌群与肝癌.pptVIP

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  • 2026-05-12 发布于山东
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Gutmicrobiome–mediatedbileacidmetabolismregulateslivercancerviaNKTcells

INTRODUCTIONPrimarylivertumorsandlivermetastasiscurrentlyrepresenttheleadingcauseofcancer-relateddeathsTheliverintimatelycross-talkswiththegutDiseasedliversareoftenassociatedwithalteredgutbacterialcomposition,ordysbiosis

ithasbeensuggestedthatgutbacterialproductscontributetomalignanttransformationofhepatocytes.gutcommensalbacteriaareimportantregulatorsofantitumorimmunitytheroleofgutbacteriainantitumorsurveillanceintheliverispoorlyunderstood

RATIONAL

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