贫血课件.ppt

Introduction Diagnosis: Physical examination Pale (lip, palpebral conjunctiva, finger nail ) accompanying symtoms hemolytic bleeding infiltration infection malnutrition * * ANEMIA Tongji Medical College, Huazhong University of Science and Technology Anemia is a commonly encountered clinical symptom that is caused by an acquired or hereditary abnormality of red blood cells (RBC) or its precursors, or may be a manifestation of an nonhematologic disorder hematologic adj. hematology n. Definition Anemia is defined as a decrease in the circulating RBC or hemoglobin and a corresponding decrease in the oxygen-carrying capacity of the blood. Normal values of the hemogram: TEST WOMEN MEN HCT (%) 37-43 42-49 Hb (g/L) 11.3-13.5 12.7-15.3 RBC Count(1012/L) 3.83-4.83 4.29-5.58 HCT:Haematocrit Hb:hemoglobin Definition A decrease in any of these values (HCT, Hb, RBC count) is called anemia. TEST WOMEN MEN HCT (%) ＜ 37 ＜ 42 Hb (g/L) ＜ 110 ＜ 120 RBC Count(1012/L) ＜ 4.0 ＜ 4.5 They can be altered by the plasmatic volumes . Difference between women and men values are due to androgen hormones. For pregnant women, Hb＜100g／L cell morphological classification cell morphological type MCV（fl） MCHC (%) Macrocytic anemia ＞100 32～35 Normocytic anemia 80～100 32～35 Microcytic hypochromic anemia ＜80 ＜32 MCV：mean corpuscular volume ； MCHC：mean cell hemoglobin concentration Macrocytic anemia Megaloblastic anemias ( folic acid and v