聚乙烯醇滴眼液用聚乙烯醇的研制.pdfVIP

聚乙烯醇滴眼液用聚乙烯醇的研制 摘 要 聚乙烯醇滴眼液用聚乙烯醇是一种以聚乙烯醇为药性成分，加以适量抑菌剂的 滴眼液。这种滴眼液能够起到湿润眼睛，减轻眼部干涩，缓解眼部疲劳的作用。本 论文以工业聚乙烯醇生产工艺流程为依据，通过小型实验合成聚乙烯醇，系统考察 了醋酸乙烯酯聚合过程中不同条件如单体的精制方法、引发剂精制方法、甲醇与单 体VAc配比、聚合温度以及单体乙酸乙烯酯转化率对产品粘度、平均聚合度及产品 性状质量等的影响。实验结果表明，采用减压蒸馏精制单体，引发剂使用无水乙醇 精制，甲醇与单体VAc配比在5:1,聚合温度稳定在60±2℃时，能够得到最好的聚 合结果。 关键词：聚乙烯醇，醋酸乙烯酯，聚合，引发剂，粘度 - 1 - 聚乙烯醇滴眼液用聚乙烯醇的研制 Abstract Polyvinyl alcohol drip eyes liquid whether one regard polyvinyl alcohol as nature composition with polyvinyl alcohol, restrain dripping the eyes liquid of fungus pharmaceutical in right amount . This kind drip eyes liquid can get up moist eyes, lighten eye do astringent , alleviate eye tired function. This thesis takes the industry polyvinyl alcohol produces the technological process as a basis, formate the polyvinyl alcohol through the small-scale experiment, system investigate acetic acid ethylene ester gets different terms of the course together such as the single refined method, refined method of initiator, methyl alcohol and single VAc matching, getting temperature and single second sour ethylene ester conversion ratio together to viscidity of the products, influence of getting degree and products properties quality together etc. equally. The experimental result indicates, it is refined and single to adopt the distillation of reducing pressure, the initiator uses the anhydrous ethanol refinedly, methyl alcohol and single VAc matching in 5:1, get temperature together to be steady to when 2 of 60 ℃, can receive the best result of getting together. Keyword: Polyviny