血压水平对脑血管血液动力学检测指标的影响.pdfVIP

·174· ChinJPrevContrChronNon-comm unDis,August2005,Vol13,No.4 二 哈D万长不弓于乡匕 . 文章编号:1004-6194(2005)04-0174-04 血压水平对脑血管血液动力学检测指标的影响 沈凤英，黄久仪，王桂清，杨永举，牟维艳，王艳，郭佐 (上海市脑血管病防治研究所，上海 201318) 摘要:目的 探讨不同血压水平对脑血管血流动力学指标(CVHI)的影响。方法 在1994年开始建立的24475例卒 中队列人群中，选择60-65岁的人群共2987例，分别按基线调查时的收缩压和舒张压水平分成8组，比较不同组间基线调 查时检测的CVHI差异。结果 脑血管平均血流速度(Vmean)、最大血流速度、最小血流速度随着收缩压和舒张压水平的升高 而显著降低，Vmean减低最大幅度分别为4.62cm/s和5.74cm/s，脉搏波速、外周阻力(RV)、特异性阻抗、动态阻力、临界压 水平以及舒张压与临界压的差值随着收缩压和舒张压水平的升高而显著升高，RV升高最大幅度分别为66.53kPa*s/m和 93.37kPa*s/m。各组间CVHI的差别均有统计学意义(P0.01)。结论 收缩压和舒张压对CVHI均有显著的影响，随着血压水 平的增高，CVHI异常的程度呈现渐进加重的趋势。从脑血管的血液动力学角度，理想的血压水平应不超过130/90mmHgc 关键词:血压;血流动力学;脑血管疾病 中图分类号:R541.3 文献标识码:A TheEffectofBloodPressureonCerebralVascularHemodynamicIndexesSHENFeng-ying,HUANGJiu-yi,WANGGui- qing,etal.ShanghaiInstituteofCerebralVascularDiseasePreventionandCure,Shanghai201318,China Abstract:ObjectiveToprobetheeffectofbloodpressureoncerebralvascularhemodynamicindexes(CVHI).Methods2987 participantsaged60to65yearswereselectedfromastrokecohortwith24475populationssetupin1994,whichweredividedinto8 groupsaccordingtosystolicanddiastoliclevelofbaselineinvestigation.DifferencesofCVHIsduringbaselineinvestigationbetween variousbloodpressuregroupswerecompared.ResultsCVHIs,suchasVmean,VmaxandVmin,weresignificantlydeceasedwith bothsystolicanddiastolicbloodpressureincreased.ThemaximalrangeofVmeandecreased4.62and5.74cm/s.However,indexes suchasWV,RV,Zcv,DR,CPandDPweresignificantlyincreasedalongwithsystolicanddiastolicbloodpressureincreased.The maximalrangeofRVincreased66.53and93.37kPa*s/m.ThereweresignificantdifferencesofCVHIsbetweengroups(P0.01). ConclusionBothsystolicanddiastolicbloodpressureaffectedonCVHIs.ThetrendofCVHDindexesabnormal