子宫腺肌病的治疗现况.pdfVIP

国际妇产科学杂志20 10 年10 月第37 卷第5 期 J Int Obstet Gynecol October 2010 Vol. 37 No. 5 355 综 述 宫腺肌病的治疗现况 江小香综述 项双卫审校 揖摘 要铱 子宫腺肌病治疗方法有药物和手术治疗遥临床常用药物有促性腺激素释放激素激动剂尧口服 避孕药尧雄激素类衍生物尧孕激素类和米非司酮 芳香化酶抑制剂和环氧化酶2 抑制剂对子宫腺肌病的疗效 正在探讨中 抗侵袭尧抗血管生成药物尧受体干预和基因治疗会逐步用于子宫腺肌病治疗遥手术治疗包括根治 手术和保守手术遥根治手术即为子宫切除术 保守手术包括子宫内膜切除术尧子宫腺肌瘤或子宫病灶切除术尧 盆腔去神经 配治疗术尧腹腔镜下子宫动脉阻断术尧子宫动脉栓塞术及磁共振引导下超声聚焦手术等遥 揖关键词铱 腺肌瘤曰 子宫肿瘤曰 药物疗法曰 妇科外科手术 Current Situation of the Treatments for Adenomyosis JIA NG X iao -xiang XIA NG Shuang-wei. Dep artment of Obs tetrics and Gynecology of Fuj ian Medical Univ ers ity Union Hosp ital, Fuz hou 350001, China Corresp onding author: JIA NG X iao-xiang, E-mail 院sop hia1904 @126.com 揖Abstract 铱 Two treatments for adenomyosis are by pharmacology and surgery. The clinical commonly used medicines are gonadotropin-releasing hormone agonists, oral contraceptives, androgen derivatives, progesterone hormones, mifepristone; the efficacy of aromatase inhibitors and cycloo-xygenase-2 inhibitors for adenomyosis is being studied now; anti-invasion medicines, anti-angiogenesis medicines, receptor interference and gene therapy will be gradually used for the treatments for adenomyosis. Surgical treatments for adenomyosis includes radical surgery and conservative surgery. The radical surgery is hysterectomy. The conservative surgery includes endometrial resection, myometrial adenomyomas or uterine lesion resection, pelvic denervation surgery, laparoscopic uterine artery blockage, uterine artery embolization and magnetic resonance guided focused ultrasound surgery 渊MRgFUS冤 and so on. 揖Key words 铱 Adenomyoma; Uterine neoplasms; Drug therapy; Gynecologic sur