模拟失重条件下与听觉方位区分联系的脑电位变化.pdfVIP

第 14 卷 　第 2 期 　　　　　　　　 　　航天医学与医学工程 　 　　　　　　　　Vol. 14 　No. 2 　2001 年 　4 月 　 　　　　　　　Space Medicine Medical Engineering 　　　　　　 　Apr. 2001 　 模拟失重条件下与听觉方位区分关联的脑电位变化 赵 　仑 ,魏金河 ,任 　维 (航天医学工程研究所 ,北京 100094) 摘要 : 目的探明模拟失重条件下听觉方位区分的脑反应特性 ,进一步了解模拟失重条件下脑功能的变 ( ) ( 化特点。方法 14 名右利手正常被试者以头低位倾斜 - 10°, HD T 模拟失重 , 头高位倾斜 + 10°, HU T) 为对照。要求被试者对声音信号进行音调选择方位区分。结果 靶和非靶信号均产生了明显的事 ( ) 件相关电位 ERPs ;与 HU T 相比 ,HD T 条件下 ERPs 的变化表现为慢电位的负向偏移; ERPs 的变化 有一定的方位和脑区特征 , 即以右后方位的 T2ERPs 受影响最大 ,右前方位受影响最小 ,且 T 和 N T2 ERPs 均以 F5 区受影响最大。结论 HD T 对听觉方位区分时脑功能状态有一定的影响。 关键词 :失重模拟 ;听觉;方位区分 ;事件关联电位 ;脑电图 中图分类号:R852. 22 　　文献标识码 :A 　　文章编号 :100220837 (2001) 0220097205 Changes of Brain Potentials Related to Auditory L ocation Discrimination during Simulated Wei ghtless2 ness . ZHAO Lun , WEI Jin2he , REN Wei. Space Medicine Medical Engineering ,2001 ,14 (3) :97～101 Abstract : Objective To study changes of brain response in distinguishing auditory location during simulated weightlessness. Method The event2related potentials ( ERPs) during auditory location discrimination were compared between head down tilt ( HD T) and head up tilt ( HU T) conditions among 14 healthy subjects. Result ( ) get ( T) and non2target (N T) auditory signals induced significant ERPs ; (2) The 1 Both the tar slow potential was significantly lower for both T and N T2ERPs during HD T as compared with that during HU T ; (3) The reduction of mean slow potential amplitude during HD T was more significant for the target signals from right2rear position and lightest for the target signals from right2front position. This phe2 nomenon was more remarkable at left2front area. Conclusion These data provide further evidence that the higher brain function was affected by simulated weightlessness. Key words : weigh