超高效液相色谱-串联质谱法测定牛奶中土霉素残留的不确定度评估.pdfVIP

5 2 Vol. 5 No. 2 2014 2 Journal of Food Safety and Quality Feb. , 2014 - * 崔向云 , 张雪峰, 袁凤琴, 李 照, 常建军, 宋晓东 ((), 011500) 摘 要: 目的 -方法 , , 结果 0.049 μg/g , 0.0036 μg/g(k=2) , 结论 -, , 关键词: ; -; ; Uncertainty evaluation of oxytetracycline in liquid milk by ultra performance liquid chromatography-tandem mass spectrometry * CUI Xiang-Yun , ZHANG Xue-Feng, YUAN Feng-Qin, LI Zhao, CHANG Jian-Jun, SONG Xiao-Dong (Inner Mongolia Mengniu Dairy Industrial Co. Ltd., Hohhot 011500, China) ABSTRACT: Objective To establish a mathematical model of uncertainty evaluation for the determina- tion results of oxytetracycline in liquid milk by ultra performance liquid chromatography-tandem mass spec- trometry method. Methods The sources of uncertainty of the whole determination procedure were analyzed and the combined uncertainty was finally obtained. Results The expanded uncertainty of 0.0036 μg/g (k=2) with 0.049 μg/g of the content of oxytetracycline was derived. The major sources of uncertainty of mea- surement included the repeatability of detection and the curve fitting. Conclusion It is necessary to control experimental conditions and the linear of standard curve to make sure the testing results are accurate. KEY WORDS: oxytetracycline; ultra performance liquid chromatography-tandem mass spectrometry;