肝癌肝动脉超选择栓塞化疗的临床应用.docVIP

肝癌肝动脉超选择栓塞化疗的临床应用 The Clinical Application of Ssuperselective Embolism Chemotherapy Transhepatic Artery for Hepatic Carcimoma 何泽清 刘国庆 汪明全 刘兴华 罗江平 He Zeqing, Liu Guoqing, Wang Mingquan, Liu Xinghua, Luo jiangping 重庆三峡中心医院CT、MR科 （中国 404000） Department of CT/MRI, Chongqing Three Gorges Central Hospital （China 404000） 中图分类号：R735.7 文献标识码：A 文章编号：1818－0086（2011）05 摘要：目的 探讨经肝动脉超选择栓塞化疗在肝癌治疗中的临床应用价值。方法 回顾性分析介入法冶疗的639例肝癌患者，对其中312例采用超选择肝动脉栓塞化疗的病例分析造影征像，碘油沉积情况及冶疗效果。结果 312例肝癌患者肝动脉造影显示，289例肝癌血管丰富，肿癌染色明显，边缘可见，其中巨块型158例，结节型112例，弥漫型42例。术后一月CT复查，117例碘油致密填塞（其中32例肿块缩小，85例肿块无变化），195例未致密填塞（52例肿块增大，143例肿块大小无变化）。临床随访1年、2年、3年以上生成率分别为84.93%（265/312），69.22%（216/312），53.84%（168/312）。结论 肝癌肝动脉超选择栓塞化疗，临床疗效显著，应作为一项重要的非手术治疗手段。 关键词：肝癌;超选择栓塞化疗;治疗 Abstact：Objective To investigate the clinical value of trans-arterial chemoembolization (TACE) for hepatic carcinoma. Methods Retrospectively analyzed the data of 639 patients with hepatic carcinoma received interventional therapy, angiographic signs, lipiodol-deposited features and treatment effectiveness in 312 cases received TACE were analyzed. Results Among 312 cases received hepatic arteriography, 289 cases had abundant blood vessels, stained obviously, had visible border. In 289 cases, the lesions were classified into three types, giant mass type (158), nodular type (112), and diffuse type (42). CT were performed one month later post-TACE, lipiodol fulfilled completely in 117cases (among them, the mass decreased in 32 cases, 85 cased had no change), lipiodol deposited partly in 195 cases (among them, the mass enlarged in 52 cases, 143 cased had no obviously change in size ), respectively. Clinical follow-up 1 year, 2 years, and more than 3 years after TACE, the survival rate were 84.93% (265/312), 69.22% (216/312), 53.84% (168/312), respectively. Conclusion TACE for hepatic carcinoma had evident treatment effectiveness, and should become one important non-surgical operation therapeutic means. Key words：Hepatic carcinoma；Superselective e