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Anal. Chem. 1994, 66, 4142-4149
Laser-Induced Fluorescence Detection of a Single
Molecule in a Capillary
Yuan-Hsiang Lee, Russell G. Maus, BenW. Smith, and James D. Winefordner*
Department of Chemistry, University of Florida, Gainesville, Florida 3261 1-7200
The objective of this work is to develop a novel laser- reduction in the probe volume can be achieved by optically
excited spectrometric method to reliably detect a single restricting the illuminated and/or observed volume, by physically
molecule in a
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