系统生物学和中医证研究.docVIP

第二届国际系统生物信息与中医药学术研讨会 报名回执表 单位名称 单位地址 邮政编码 姓 名 职 务 性别 民族 联系电话 电子邮件 食宿（打√） A.统一安排 B.自理 注：1. 请参会代表务必填写报名回执表，传真至：021E-mail至组委会，以便安排食宿； 2．应征论文题目、姓名、关键词、摘要等需中英文对照，请参见上届《论从》格式，将论文全文发E-mail至：fangzheng2010@126.com； 3．没有论文的代表也可报名参会。 系统生物学和中医证的研究 沈自尹* 复旦大学附属华山医院中西医结合研究所（上海 200040） [摘要] 本文对自15世纪下半叶以来科学思想和科学方法论的回顾，阐明还原论是研究存在的科学，而涌现论则是生成的观点，科学的态度是把还原论和整体论结合起来。指出系统生物学理论和分子生物学相结合以及数学建模的方法是生命科学研究的新趋势，而“证”的研究正好和这个处于科学前沿、综合程度很强的系统生物学理论相结合，将几十年来用还原论方法在分子水平的研究成果用生物数学方法进行系统整合，将再次把“证”的研究推向科学前沿。 [关键词] 系统生物学 还原论 涌现论 证 数学建模 Systems Biology and Studies on the ZHENG of TCM SHEN Zi-Yin Institute of integrated traditional Chinese and western medicine Huashan hospital affiliated to Fudan University (Shanghai, 200040China) [Abstract] The idea of science and methodology of science since the later half 15th century was reviewed in this article. The great difference between reduction theory, which is used to study the components and nature of things, and emergence theory, which is mainly involved in studying the production of new things was precisely discussed. The better method in research work is to combinate these two theorys. The author pointed out that the combination of systems biology and molecular biology and application of mathematical modeling is a new trend in biology science. The connotation of ZHENG, a professional term of traditional Chinese medicine, is consistent with systems biology. The integration of findings at molecular level during the last several decades by reduction theory will push the research of ZHENG into the scientific frontier again. [Key words] systems biology, reduction theory, emergence theory, ZHENG, mathematical modeling [参考文献] [1] 许国志.系统生物学[M].上海:上海科技教育出版社,2000:1-33 [2] 沈自尹.同病异治和异病同治[J].科学通报,1961,(10):51-53 [3] 沈自尹.对祖国医学肾本质的探讨[J].中华内科杂志,1976,(2):80-83 [4] 沈自尹,陈剑秋,陈响中,等. 老年人和“肾阳虚”患者的甲状腺功能对比观察[J]. 中西医结合杂志,1982,2(1):9-11 [5] 沈自尹,王文健，陈响中，等.肾阳虚证的下丘脑-垂体-甲状腺、性腺、肾上腺皮质轴功能的对比观察[J].医学研究通讯,1983,(10):1-16 [6] 沈自