第九章 线粒体遗传病72138.pptVIP

4. Reduction of mtDNA copy number mtDNA Mutation Disease 3. Insertion OR deletion mutation 2. Protein synthesis mutation——tRNA 1. Missense mutation Aging Genetic Characteristics of mtDNA mtDNA Mutation Disease Emphasis Replicative segregation: Heteroplasmy Homoplasmy 1. Semi-independent 2. Non-universality of the genetic code 3. Matrilineal inheritance 5. Threshold value 6. High mutation rate Genetic Characteristics 4. Reduction of mtDNA copy number mtDNA Mutation Disease 3. Insertion OR deletion mutation 2. Protein synthesis mutation——tRNA 1. Missense mutation 第九章 线