细胞色素C对庆大霉素、依替米星致大鼠肾小管毒性预防作用与研究.pdf

目 录 英文缩略词表（Abbreviations）·······························1 中文摘要 ···················································2 ·························5 英文摘要（Abstract）··············· 前 言 ·····················································9 第一部分 细胞色素 C 对庆大霉素致大鼠肾小管毒性的预防作用研究 ························11 1 仪器与材料···················· 2 方法··················································12 ·························14 3 结果························· 4 讨论··················································17 ··························20 5 结论························ 第二部分 细胞色素 C 对依替米星致大鼠肾小管毒性的预防作用研究 1 仪器与材料············································21 ·······················22 2 方法··························· 3 结果··················································25 ························33 4 讨论·························· 5 结论··················································36 ··························37 参考文献 ························ 附 录 ····················································44 ·······························45 致 谢 ····················· 综 述 中药防治药源性肾毒性的研究现状··························47 参考文献（综述部分）······································81 英文缩略词表（Abbreviations ） 英文缩写 英 文 全 称 中 文 名 称 AGs aminoglycosides 氨基糖苷类抗生素 AIN acute interstitial nephritis 急性间质性肾炎 AKI acute kidney injury 急性肾功能损伤 Apaf-1 apoptotis protease activating factor-1 凋亡蛋白酶活化因子-1 ARF acute renal failure