SNP基因型分析.pdfVIP

® PRODuCT bulleTIn TaqMan Genotyping Assays ® TaqMan SNP Genotyping Assays ® TaqMan SNP Genotyping Assays from Applied Biosystems provide a highly flexible technology for detection of poly- morphisms within any genome. With the simplest workflow available, TaqMan® Assays are the quickest way to generate genotyping data. Based on powerful TaqMan® probe and primer chemistry and designs, and coupled to dependable Applied Biosystems instruments and software, these Made-to-Order assays produce high-confidence results. These TaqMan Assays are ideal for genotyping applications including screening, associa- tion, candidate region, candidate gene, Powerful, Proven Chemistry (MGB) technology at the 3’ end, or fine-mapping studies. Whether your genotyping studies deliver superior allelic discrimination. require targeted detection of essential The MGB molecule binds to the minor Content-rich marker-selection tools SNPs, or the flexibility for choosing groove of the DNA helix, improving simplify study design and help you SNPs for mapping, TaqMan SNP hybridization-based assays by stabilizing select from a library of human and Genotyping Assays are the technology the MGB-probe/template complex. The mouse assays. This library includes of choice. Proven TaqMan probes, which increased binding stabilization permits over 4.5 million genome-wide human incorporate minor groove binder the use of probes as short as 13 bases assays (of which 3.5 million a