呼吸机相关性肺炎患者病原菌分布及耐药情况研究.pdfVIP

中国现代医生 2014年8月第52卷第23期 窑临床研究 窑 呼吸机相关性肺炎患者病原菌分布及耐药情况 研究 方红伟1 秦 勇1 郭向东2银 1.石河子大学医学院第四附属医院呼吸科袁新疆阿克苏 843000曰2.石河子大学医学院第四附属医院感染科袁新疆阿克苏 843000 [摘要] 目的探讨医院呼吸机相关性肺炎渊VAP冤病原菌分布及耐药情况袁以便更好地指导临床用药遥 方法 回顾性 分析我院收治的598例机械通气患者的临床资料袁 从中筛选VAP患者并对其下呼吸道分泌物病原菌进行培养 并鉴定结果遥 结果221例VAP患者下呼吸道痰液共分离出251株病原菌袁其中革兰阴性菌与阳性菌分离率分别 占71.3%与17.9%曰革兰阴性菌与阳性菌分别以鲍曼不动杆菌与金黄色葡萄球菌分离率最高遥鲍曼不动杆菌泛耐 药菌株的检出率最高袁 达27.9%袁MRSA和MRSE检出率分别为66.7%和61.5%遥 结论VAP的病原菌以革兰阴 性菌为主袁相关菌株耐药性逐渐增高袁应及时监测相关病原菌耐药性遥 [关键词] 呼吸机相关性肺炎曰病原菌曰耐药 [中图分类号] R446.5 [文献标识码] B [文章编号] 1673-9701渊2014冤23-0013-03 Distribution and drug resistance of pathogens in patients with ventilator- associatedpneumonia 1 1 2 FANG Hongwei QIN Yong GUOXiangdong 1.Departmentof Respiration, the 4th Affiliated Hospital of Medical College of Sihezi University, Aksu 843000,China曰 2.Department ofInfectious,the4th Affiliated Hospitalof Medical Collegeof ShiheziUniversity,Aksu 843000,China [Abstract]ObjectiveTo investigatethe distribution and drug resistance pathogensfrom ventilator-associated pneumo鄄 nia 渊VAP冤patientsfor to better guide clinicaltreatment. Methods The medical records of 598 mechanical ventilation patients were retrospectively reviewed and the results of sputum culture and antibiotic resistance of pathogens from VAP patients were analyzed. Results The 251 strains of pathogens were isolated from lower respiratory tract sputum specimens in 221 patients with ventilator-associated pneumonia. Among them袁the isolation rate of the gram-negative bacteriawas the highest 渊71.3%冤袁followed by the gram-positive bacteria 渊17.9%冤.The Acinetobacter baumannii and Staphylococcus were the top species in gram-negative and