复方芪麻胶囊治疗气虚痰浊型单纯收缩期高血压病60例临床观察_临床医学论文.docVIP

复方芪麻胶囊治疗气虚痰浊型单纯收缩期高血压病60例临床观察_临床医学论文 复方芪麻胶囊治疗气虚痰浊型单纯收缩期高血压病60例临床观察_临床医学论文 作者：靳利利,丁达 郭英普,黄培红,王清海 【摘要】 【目的】观察复方芪麻胶囊治疗气虚痰浊型单纯收缩期高血压病(ISH)的临床疗效。【方法】选择符合WHO/ISH高血压诊断标准的120例ISH患者,随机分为2组。治疗组60例采用复方芪麻胶囊治疗,对照组60例采用硝苯地平缓释片治疗。2组疗程均为 1个月。观察2组的降压疗效和中医证候疗效,比较2组治疗前后血压、24h动态血压的变化,并评价其安全性和不良反应。【结果】(1)疗效方面：降压总有效率治疗组为73对照组为78组比较差异无显著性意义(Pgt;0中医证候疗效总有效率治疗组为95对照组为73组比较差异有显著性意义( 0。(2)血压变化方面：治疗后2组收缩压(SBP)较治疗前均明显下降(0或0但治疗后2组间比较差异无显著性意义(Pgt;0。治疗后2组的24h动态血压各项指标均明显改善(与治疗前比较,0其中对照组24h舒张压(DBP)、昼DBP、夜DBP下降幅度更明显(与治疗组比较，0。(3)安全性和不良反应方面：治疗过程中对照组有3例轻度不良反应,未影响继续治疗。【结论】复方芪麻胶囊可以有效降低气虚痰浊型单纯收缩期高血压病患者的收缩压,缩小脉压差,且能明显改善患者的临床症状,是治疗单纯收缩期高血压病的有效中药制剂。 【关键词】 高血压/中药疗法;复方芪麻胶囊/治疗应用 单纯收缩期高血压(isolated systolic hypertension,ISH)为常见高血压病之一,以老年人多见,近年来其发病呈快速增长趋势。据流行病学统计,ISH 的患病率在我国已大于1占老年高血压病总人数半数以上[1],在临床上备受关注。中医本无高血压病名,根据患者主诉和症状，辨证属“眩晕”、“头痛”、“中风”等范畴。大量临床资料观察发现,ISH以气虚痰浊型较为多见[2],故本研究采用中药制剂复方芪麻胶囊治疗,并与西药硝苯地平缓释片进行对照观察。现将研究结果报道如下。 　　1资料与方法 　　1临床资料选择2008年3月～2009年6月广东省第二中医院心血管科门诊和住院病例共120例,随机分为治疗组和对照组各60例。治疗组中,男35例,女25例;年龄60～80岁,平均65岁;病程5～20年,平均1162年;ISH分级：1级22 　　observed before treatment, and after one and two treatment course(s). The adverse reaction was recorded during the treatment. Results At the end of the first treatment course, the scores of ESS and ADL were improved in both groups (0 001 compared with those before treatment), but the differences of ESS score, ADL score and their score increasing percentages between the two groups were insignificant (Pgt;005).At the end of the second treatment course,the scores of ESS and ADL were markedly improved in both groups (001 compared with those before treatment), and the differences of ESS and ADL scores and their increasing percentages between the two groups were significant (005). Conclusion Edaravone combined with PIS has a better effect on relieving neurologic impairment symptoms of patients with acute cerebral infarction than PIS alone. 　　Key words: EDARAVONE/therapeutic use;PLANTULA IXERIDIS SONCHIFOLIAE/therapeutic use; CEREBRAL INFARCTION/TCW 　　ACTIVITIES OF DAILY