儿童脑室周围白质软化症的弥散张量成像的研究.pdfVIP

‘l 36· 2004Annual ofChineseMedical Symposium ImagingTechnology 儿童脑室周围白质软化症的弥散张量成像研究 tensor of Diffusion with leukomalacia imagingpediatric periVentricular patients 谢晟。，郭雪梅，崔爱国，肖江喜，蒋学祥 (*北京大学第一医院放射科，北京100034) [摘 要] 目的 应用弥散张量成像对儿童脑室周围白质软化症患儿和正常婴幼儿进行比较。方法 对15例正常志 愿者和15例PVL患儿进行了盼散张量成像扫糍，测量双侧内囊后肢、双侧视放射和肼胝体膝部．压部的部分各向异性 FA值，并对结果进行统计学比较。结果对照组和PVL组的双铡内囊后肢、双伽视放射和辫胝体膝部、压部的部分各 向异性均存在显著性差异(Po．01)。结论弥散张量成像船提示纤维束的髓鞘化过程的延迟，反映儿童发育中脑白 质微观结构的改变，在PVL的随访观察中具有较大的潜力。 [关键词]弥散张量成像，儿童脑室周围白质软化症 Ieukomalaeia(PVL)withnormal To with children patients [Abstract]Objectivecomparepediatric periventricular were in15 PVL tensor MethodsDiffusiontensor obtained with and15 diffusion pediatricpatients sing imaging images thefraetlonat normal ofinterestweredrawntomeasure hilateraI children．Regions anisotropy(FA)oIposte。 age-matched riotlimbofinternal of caliosumand of caliosumThevalV capsule，bilateralopticradiation，genucorpus spleniumcorpus uesofPVL andnormalchildrenwere t-test，ResultsTheFAvaluesof patients eomparedusingnon—dependentsamples in were inPVL thannormal ofinterest lower significantly regions prescribed patients of inPVL Diffusiontensor revealretard offibertracts canbea tooline—