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倍他洛克对老年开胸手术患者围术期心脏并发症的影响.doc
倍他洛克对老年开胸手术患者围术期心脏并发症的影响
赖仁纯 许梅曦 黄文起 王旭东 曾维安 林文前
【】【】s of Betaloc on Cardiac Events in the Elderly Patients Undergoing Thoracic Surgery
LAI Ren-chun﹡ ,XU Mei-xi﹡ ,HUANG Wen-qi,et al﹡. Department of Anesthesiology, Cancer center, Sun Yat-sen University ,Guangzhou 510060,China
【】GroupⅠreceived betaloc. Group Ⅱ received N.S. The patients in groupⅠreceived betaloc to control heart rate from anesthesia induction to 72 hours after surgery. Some data including perioperative hemodynamic date, the level of cardiac troponin T, perioperative cardiac events ,the numbers of postoperative sinus tachycardia were recorded. Results During anesthesia induction、intubation or extubation , HR or systolic arterial pressure was significantly lower than preoperative values in group Ⅱ (P0.05). Hemodynamic data were satisfactory in group Ⅰ (P0.05); Elevated levels of cTnT occurred in three patients in groupⅡ on the 1st and 3rd days after surgery. Levels of cTnT were negative in all patients in groupⅠ. There were no significant differences between two groups (P=0.237); None of groupⅠsuffered cardiac events. Six patients in group Ⅱ suffered cardiac events. There were significant differences between two groups (P=0.024). Two patients in group Ⅱ suffered myocardial ischemia. No one in groupⅠsuffered myocardial ischemia (P0.05). No one in two groups experienced myocardial infarction and death; One patient in group Ⅱ suffered atrial fibrillation during the operation, three patients suffered it after surgery. None found in groupⅠ(P0.05); Tachycardia happened to 15 patients in group Ⅱ and 6 patients in groupⅠ. There were significant differences between two groups (P0.05). Conclusions Betaloc can reduce the incidence of perioperative cardiac events in the elderly patients undergoing thoracic surgery. Betaloc can reduce the incidence of postoperative tachycardia in the elderly patients undergoing thoracic surgery. Betaloc can restrain the effects of tracheal intubation or extubation on hi
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