大孔树脂脱除冬凌草提取物中色素的工艺研究.pdfVIP

孙源谦, 礼 彤, 王立红, 郭永学, 张少华, 周丽莉 ( 沈阳药科大学 制药工程学院, 辽宁沈阳1100 16) : : 探索大孔 脂脱除冬凌草提取物中色素的可行工艺: 以冬凌草中叶绿素的含量为 指标, 采用静态吸附- 解吸和动态吸附- 解吸实验, 对5 种 脂的脱色效果脱色条件 脂再生方法进 行比较和筛选: 确定HZ- 803 为脱色用 脂, 乙酸乙酯作为洗脱剂在吸附流速为3 BV h - 1 , 解 吸流速为5 BV h- 1 , 脱色率可达90% , 经过15 次循环使用, 脱色率仍在70% 以上: H Z- 803 大孔 吸附 脂对冬凌草提取物中色素具有良好的吸附和解吸性能 : 冬凌草; 叶绿素; 大孔吸附 脂; 吸附; 解吸 : R284. 2 : A : 1673-2197( 2011) 04- 0030- 03 Separation of Chlorophyll in Extract of Rabdosia Rubescens by Macroporous Resins * Sun Y uanq an, L T o ng , Wang L hong, Guo Y ongx ue, Zhang Shaohua, Zhou L l ( Sheny ang Pharmaceut cal U n vers ty , L aon ng 110016, Ch na) Abstract: Objective: A feas b l ty pro cess w as stud ed to separ ate chlo rophyll fr om the ext ract of Rabdo s a rubescens by macro- po rous res ns. Methods: 5 ty pes of macr oporo us res ns were compared w th the absor pt on and deso rpt on propert es as deco lor ant s for the el m nat o n of chlor ophy ll by effects and cond t ons of deco lor zat on and regenerat on of r es ns. Results: M acr oporo us r es n H Z- 803 was selected fro m 5 types of ones by compar ng the abso rpt on and desorpt o n pr opert es as a decolor ant fo r the el m nat on of chlo rophy ll, ethy l acet ate as for eluent . T he opt m zat on of pr ocess cond t ons w as stud ed w t h abso rpt on flo w r ate 3 BV h- 1 ; de- sorpt on flo w r ate 5 BV h- 1 ; decolor zat on r at o for o nce w as 90% ; after 15 c r culat ons the deco lo r zat on rat o was st ll above 70% . Conclusion: M acropor ous r es n H Z- 803 was selected for t he superperfo rmance of the absor pt o n and deso rpt on pr oper t es as a decolor ant fo r the separatat on of chlo rophyll fr om Rabdos a r ubescens. Key Words: Rabdosia R ubescens ( H ems l. ) H ar a;