中药复方物质基础研究新思路和方法.pdfVIP

• 420 • ( ) 中华中医药杂志 原中国医药学报 2008年5月第23卷第 5 期 CJTCMP , May 2008, Vol .23, No.5 ·思路与方法· 摘要： 关键词： New thoughts and methods of studying material base of traditional Chinese herbal formula 1 1 1 1 1 2 JIA Xiao-bin , CHEN Yan , LI Xia , TAN Xiao-bin , FAN Chen-yi ,LI Lian-da 1 ( Key Laboratory of New Drug Delivery System Applied Technology of Chinese Materia MedicaJiangsu Provincial Academy 2 of Chinese Medicine, Nanjing 210028China China Academy of Chinese Medical SciencesBeijing 100091China) Abstract: The sophisticated chemical constituents are potential basis of Chinese herbal formula in preventing, treating and diagnosing diseases. On the basis of understanding potentially material base of Chinese herbal formula from traditional and modern theories, we propose a new view of “functional constituents”. The chemical constituents of Chinese herbal formula could be divided into three parts: effective constituents, functional constituents and ineffective constituents. The potentially material base of Chinese herbal formula is composed by the effective constituents and the functional constituents and has “three layers and multi-dimensional structure”. In this paper, two different schemes were proposed to investigate the integral structure of potentially material base of Chinese herbal formula from “microscopy to macroscopy” and “macroscopy to microscopy”. Key words: Material base; Effective constituents; Functional constituents; Three layers and multi-dimensional structure