BAFF、BAFF-R在滤泡性淋巴瘤的表达及其与临床病理特征与预后的关系.pdfVIP

理岱胜瘤匿堂呈Q!!生!旦笙至!鲞擅刊 丛Q堕垦盟Q盟垦Q垦Q鱼!：量!乜：兰Q!≥：yQ坠21：盟Q：量坠巳乜! 。109· 关系 闻淑娟1’3，李亚军1’2，李苏1’2，黄嘉佳1’2，夏奕1’2，姜文奇1’2 0fBAFFandBAFF—Rinf0¨icular w¨h EXpreSSion Iymphoma：correIationc¨niC0pafh0- CharaCfer．对icsandsurViValoutcomes 109iC Wen Shujuanlr，LiYajunl’．，LiSul’-，HuangJiajial’-，XiaYil，-，JiangWenqil，2 Sen踟妇e邢蚵coMer＆舭r，G∽，曙d0昭砒7咿如n528400，傩im；3DePon眦mo，D印口n袱眦旷讹d如口f0MD研，4历Z池ted几mr 日0印豇“矿砌狮昭胁d地口Z魄i抛巧毋，U九正删i，830011，仇i眦． activation BAFF twomembersoftumor 【Abstract】objective：B—ceuf如tor(BAFF)andreceptor(BAFF—R)are in necrosis invitroandinvivo haveshownthatBAFF criticalmles f如tor(TNF)familv．Bothexperiments plays pmmo- B—ceU resistance and BAFF—R．E1eVat- tingmalignantproliferation，aJlti—apoptosis，anddmg bybindingactiVating edBAFFserumlevelshavebeenfoundinanumberof and B—cell hematopoietic1ymphoidmalignanciesincluding chmnic lymphocyticIeukemia(B—CLL)，non—Hodgkin，slymphoma(NHL)，Hodgkin，slymphoma(HL)，multiple was ina ofB— cellacute leukemia．BAFF—R myeloma(MM)，andpre—B lymphoblaLstic expressedvariablyvariety inf0珊ationexists andthe mleofBAFFandBAFF— expressionpmtiles prognostic ceⅡmalignancy，“mited regarding RinfbUicular todete珊inethe ofBAFFandBAFF—RinFLtumor lymphoma(FL)．wesought expI℃ssionprofiles tissueandFLceU toevaluatethecorreIationofBAFFandB