六级连续化膜生物反应工艺在炳烯酰胺生产中的应用的研究.pdfVIP

J045 1580h 99.9 434.23g/L 0.01526mol/L/min 50 CONTINUOUS SIX-STAGE HOLLOW-FIBER MEMBRANE BIOREACTOR SYSTEM USED IN BIOCONVERSION OF ACRYLAMIDE SUN Xudong, YU Huimin, SHI Yue and SHEN Zhongyao (Department of Chemical Engineering, Tsinghua University, Beijing 100084, China) Abstract A continuous process of six-stage hollow-fiber membrane bioreactor system, made of Polyvinylidene fluoride, was designed for bio-converting the acrylonitrile to acrylamide. On the research basis of single stage membrane bioreactor, the feasibility of multiple-stage continuous process was discussed. At 15 , the six-stage membrane bioreactor process was steadily lasted over 80 hours, the conversion rate of acrylonitrile was 99.9%, the concentration of acrylamide in the output solution was 434.23g/L and the productivity was 0.01526mol/L/min. Compared with the batch reaction style, in which the immobilized cell was used as catalyzer, the productivity was enhanced above 40%, meanwhile the acrylamide in output was remarkably concentrated. In the hollow-fiber membrane system, the immobilized cells were replaced by the free cells, the product, acrylamide, was separated successfully with the cells, and there were no by product, acrylic acid, been found in the product. This kind of process has a favorable foreground in industrial application. Keywords acrylamide, bioconversion, reaction coupled with membrane separation, continual reaction process szy-dce@mail.tsinghua.edu.cn; 28 ; (200345) acrylamideAM acrylonitrile, AN