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白芷提取物对延胡索镇痛的协同作用.pdf

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白芷提取物对延胡索镇痛的协同作用.pdf

Journal of Ethnopharmacology 129 (2010) 115–120 Contents lists available at ScienceDirect Journal of Ethnopharmacology j o u rn al h omepage: w w w. elsev /locate/jethpharm Correlation between synergistic action of Radix Angelica dahurica extracts on analgesic effects of Corydalis alkaloid and plasma concentration of dl-THP Zheng-Gen Liao, Xin-Li Liang ∗ , Jing-Yun Zhu, Guo-Wei Zhao, Ming Yang, Guang-Fa Wang, Qie-Ying Jiang, Xu-Long Chen Key Laboratory of Modern Preparation of TCM (JiangXi University Of Traditional Chinese Medicine), Ministry of Education, No. 18, YunWan Road, WanLi District, Nanchang, JiangXi 330004, China a r t i c l e i n f o a b s t r a c t Article history: Aim of study: : Yuanhu Zhitong prescription that consists of Corydalis yanhusuo and Radix Angelicae dahuri- Received 20 November 2009 cae has been used for the treatment of gastralgia, costalgia, headache and dysmenorrhea in Traditional Received in revised form 1 March 2010 Chinese Medicine. Our previous studies demonstrated that Corydalis alkaloid (CA, derived from the root Accepted 7 March 2010 of Corydalis yanhusu) had potent analgesic properties, and the total coumarins of Angelica dahurica (Cou) Available online 20 March 2010 and volatile oil (VO) that derived from the root of Radix Angelicae dahuricae all could increase the anal- gesic effect of CA. The major objective of this paper was to investigate the mechanism that leading the Keywords: