胰岛素泵治疗糖尿病的临床疗效观察.pdfVIP

胰 岛素泵 治疗糖尿病 的临床疗 效观 察 张斌华 华聋 夏 礼斌 摘【耍】 目的 探讨胰岛素泵在糖尿病患者治疗中的治疗效果，并与常规治疗方法进行 比较。方 法 将 98 例糖尿病患者随机分为两组 ，分别采用腆岛素泵( 即持续皮下胰岛素翰注法 ，CSII ) 持续皮下注 射门冬映岛素和每夭 3 次皮下注射双相 门冬胰 岛素治疗 ，比较两种治疗方法前后血糖 ，理想降糖所需时 间，胶岛索类似物用量 ，以及低血糖的发生率。结果 两组治疗后胶岛索各阶段血糖均较治疗前显著下 降(P 0. 0 1) ，且治疗后泵治疗组平均血糖低于3 次皮下注射治疗组 .但差异无统计学意义( P 0. 05) ; 胰岛素泵治疗组血精控制达标时间短于3 次皮下注射治疗组( P 0. 0 1) ，浪岛索类似物用量小于 3 次皮 下注射治疗组( P 0.0 1) ，且低血糖发生率也明显减少( P 0. 05) . 绪论 短期应用胰岛素泵强化治疗 可在短时间内使血糖获得理想控制;在血糖控制达标时间及映岛索类似物用t 方面优于3 次皮下注射胰 岛素类似物 ，且可有效减少低血糖发生率 。 【关性伺] 糖尿病; 眺岛素泵; 映岛素类似物:持续皮下胰岛家输注 Clinical observati on . tr eatment o diabetes with insuil n pump ZHANG Bin-huo ,HUA Qiang ,%IA Li- bin. Department o Endocrine ,Ygiahan Hospital ,Wannan Medical College , Wuhu 24 1001,Anhui , China (Abstract ] Obj ective AIMto study the e icacy o treatment with insulin pump and conventional insu- Bn in usion in p atients with diabetes. Meth ods g patients with diabetes were divided into two gro ups t46 p a- tients were treated with insulin pump co ntinuous subcuta neous insulin in usion( CSII ) ,52 patients accepted con- ventional insulin treatment( CIT) -subcuta neous insulin Aspart in usion 3 times s day. Blood glucose levels be ore and at er treatment ,duratioa to reach the obj ective gluco se level , dosage o insulin analogue and occurrence o hypoglycemia were observed. Results Blood glucose levels decreased signi icantly a ter treatment in both gro ups (P 0. 0 1) . The average blood gluco se levels a ter treatment in CSD gro up wen ound lower than those o CIT gro up 山ut no . 咖s cant di ere nce wen ound( P 0. 仍) . The duration to reach the obj ective gluco se level 恤CSII gro up were ound shorter than those o CIT gro up ,dosage o insulin analogue and re quency o by- poglyeemia reaction wen ound lower than those o CIT gro up ( P 0. 01,P 0. 0l ,and P 0. 05 re spectively) Conlc usion Continuous sub