豆豉及其多糖对A-葡萄糖苷酶抑制作用的研究.pdfVIP

The Study on Effect of Sar candra gl abr a on Prevention andTreatment of Thrombocytopenia by Chemotherapy 1 2 3 4 1 Zhong Liye , Liu Tianhao , Chen Yunxian , Zhong Xueyun ,Du Xin , 1 1 1 1 Lu Zesheng , Weng Jianyu ,Wu Suijing ,Lin Wei ( 11The Depart ent of He atology,Guangdong People. s Hospital,Guangzhou 510080; 21The Depart ent of Oncology, The Second Affiliated Hospital, Zhongshan University, Guangzhou 510120; 31T he Depart ent of He atology, T he First Affiliated Hospital, Zhongshan University,Guangzhou 510080;41Jinan University, Guangzhou 510632) Abstract Objective:To investigate the effect of S ar candr a g labr a Thunb on prevention and treat ent of thro bocytopenia af- ter che otherapy with a large dosage1 Methods:The Babl/ c ice odel of thro bocytopenia was ade by intraperitoneal injection of 5-FU at a large dosage1 All ice were poured S arcandr a g la bra Thunb dilution to the ice. s sto ach once daily fro the beginning nd th of the experi ent1Then the effect was analyzed by easuring peripheral blood cell counts of the ice on the 2 day,the 4 day and th th the 7 day after che otherapy1 On the end of 7 day, all icewere killed,and then bone arrow biopsy was e ployed to investigate the he apoietic condition1 Results: Before the che otherapy, the platelet counts of ice treated by S ar candr a g labr a Thunb were higher than that in the control group (P 0105)1 After che otherapy with 5-FU, the platelet counts were not significantly decreased in two all experi ental groups co pared with negative control group ( P 0105) ,while there was not significantly different bet