碳青霉烯类抗生素临床合理应用探讨_滕瑛珏.pdfVIP

1128 2009 10 7 10 Ch in ese Journ l of G ener lP r ctice, October 2009, Vol7, N o10 碳青霉烯类抗生素临床合理应用探讨 滕瑛珏, 高蕴秀 通过分析呼吸道常见致病菌的耐药现状和肺部细菌性感染治 中抗生素的正确选用, 为临床合理使 用抗生素类药物提供参考 主要以治 院内肺部感染为例, 以碳青霉烯类抗菌药物临床实践为基础, 参考最近国 内外相关文献资料, 分五部分进行了总结与讨论 碳青霉烯类抗菌药物对肺部细菌性感染具有广谱高效的抗菌 活性和相对低耐药率 该药物目前是院内肺部细菌性感染治 中的一线抗菌药物 碳青霉烯类抗生素; 肺部细菌感染; 治 ; 合理使用 R969. 3 R978. 1 A 2009) Discuss on RationalUse of Carbapenems in Clinic TENG YingJue, GAO YunX iu. Departm ent of GeneralM edicine,H osp ital of Z engZ ou Institute of L ig t Industry, Z engz ou 450002,H e nan, C ina Abstract Objective T o explore the drugresist nt ctu lity of common p thogen from respir tory tr ct in fections nd the proper pplic tion of ntibiotics for experienti l tre tm ent of pulm on ry b cteri l infections, hope to offer new str tegies to mi prove ntib iotics use. Methods T k ing the tre tm ent of hospit l cqu ired pneumon i ( HAP; or NP: Nosocom i l Pneum oni ) s typ ic l ex m ples, consu lting the theories nd inform tion from correl tive p pers of both dom estic nd bro d, we summ rize nd discuss the subjects b sed on clinic l using of c rb penem s ntmi icrob i l m ed icines. Results The c rb penem s re bro dspectrum, highest effective n tib cteri lm edicinesw ith lowest drugres ist nt r te for pu lmon ry b cteri l infections. Conclusion C rb pen em s re pplic ble n tmi icrob i lm edicines for HAP. K ey words C rb penem s; Pulmon ry b cteri l infections; Tre tm ent; R tion l use , - 1 , ( CAP) , , CAP 1/3, , , ( H ospit l Acquired , 90% Pneum oni , HAP) ( Nosocom i l Pneum on i, NP) ,