非酒精性脂肪肝实验研究进展_翁小刚.pdfVIP

15 11 Vol. 15, No. 11 2009 11 Chi ese Jour al of Experime tal Traditio al Medical Formulae Nov . , 2009 ## * 翁小刚, 朱晓新 , 杨 庆, 李玉洁 ( 中国中医科学院中药研究所, 北京 100700) [ ] ( NAFLD) NAFLD 80 , NAFLD NAFLD , NAFLD NAFLD ( IR) , IR / 0 NAFLD NAFLD , Kupffer NAFLD [ ] ; ; ; ; [ ] R28515 [ ] A [ ] 1005-9903(2009) 11-0104-06 Review of Experimental Studies on Nonalcoholic Fatty Liver Disease * WENGXiao-gang, ZH UXiao-xin , YANG Qing , LI Yu-j ie (Institute of Chinese MateriaMedica, ChinaAcade y fo ChineseMedical Sciences, Bejiing 100700, China) [Abstract] No alcoholic fatty liver disease ( NAFLD) is a sort of pare chymal lesio ot caused by excessive co sumptio of alcohol. It i cludes simplex fatty liver, steatohepatitis, greasy hepatic fibrosis a d cirrhosis. NAFLD e compasses a spectrum of commo hepatic disorders i co temporary society with multiple pathologic co seque ces a d is i cide ce is paralleli g the i creasi g umbers of overweight a d obese i dividuals worldwide.The pathoge esis of NAFLD is thought to be related mai ly with i suli resista ce sy drome a d oxidative stress, a d o effective drug ca be obtai ed i the market for treatme t of NAFLD. Large experime tal studies o NAFLD are i progress rece tly. This review outli es the experime tal studies about NAFLD a d the adva tage of traditio al Chi ese medici e i treatme t of NAFLD. [ Key words] No alcoholic fatty liver disease; Pathoge esis; I suli resista ce; Experime tal studies; A imal model , 5% , , 15% ~ 50% , 20% , 20% , 50% ,