银杏茶对酒精性肝损伤小鼠血清GSH-PX影响.pdfVIP

银杏茶对酒精性肝损伤小鼠血清GSH-PX的影响 许秀举 郭 燕 刘金勇 包头医学院营养食品研究所，内蒙古包头市， 014060 目的：探讨银杏茶、加硒银杏茶及加锌银杏茶对酒精性肝损伤小鼠血清血清GSH-PX活力的影响及其对肝脏保 护作用。方法： 将50只雄性昆明种小鼠随机分为5组：空白对照组、模型对照组、银杏茶组、银杏茶加硒组和银杏茶加锌 组，分别给药30d后，按试剂盒说明测定血清中GSH-PX活力。结果：与模型对照组相比银杏茶、加硒银杏茶及加锌银杏茶能 显著升高小鼠血清GSH-PX活力(P＜0.05，P＜0.01)。结论：银杏茶、加硒银杏茶及加锌银杏茶具有增强小鼠GSH-PX活 力，对其肝脏具有保护作用。 银杏茶；GSH-PX;硒；锌;酒精 InfluenceofGingkoTeaonAlcoholicLiverDamageMiceofSerum GSH-PX XUXiuJuGUOYanLIUJinYong Baotoumedicalschoolnutritionfoodinstitute,Baotou,014060,China ObjectiveTostudytheinfluenceofselenium-addedGingkotea, Zine-addedGingkoteaand commonGingkoteaonmicesglutathioneperoxidase(GSH-Px)AndtoobservewhetherGingkoteacanplaya usefulroleinAlcoholicliverdisease.Methods::50kunmingmiceweredividedinto5groups:selenium-added Gingkoteagroup,commonGingkoteagroup,zine-addedGingkoteagroup,Modelgroupandblankgroup throughweightrandomly.AfterthemicewereorallyadministeredwithGingkoteafor30days,GSH-Px activity inserumofthemiceweremeasured.Results:Comparedwiththemodelgroup,selenium-addedGingkotea, Zine-addedGingkoteaandcommonGingkoteacouldobviouslyenhancetheGSH-Pxactivity(P＜0.05,P＜ 0.01)inserumofthemice.Conclusion:elenium-addedGingkotea,Zine-addedGingkoteaandcommonGingko teacouldobviouslyenhancetheGSH-Px activityinserumofthemice,protectliverinmice. Gingkotea;GSH-Px;Se;Zn;Alcoholic 5.162--t:10.8471 ;7.702--L10.765] ;721.054-4-7_459 #肝脏病杂志，2( E酒精性肝损伤的一 iomreactiveoxyg‘