NGF_BDNF和受体trkA_trkB_trkC在正常猴脊髓的表达.pdfVIP

Sep. 200218( 3) 240242 (Chinese Journal of Neuroanatomy) NGFBDNF trkAtrkBtrkC¹ 伍校琼　李昌琪　刘　丹　蔡维君　罗学港 ( , 410078) ( NGF) , ( BDNF) NGF trkA trkBtrkC : NGF , NGF BDNF , trkAtrkB trkC ( NGF ) , BDNF trkA tr kB trkC ( ) , HE EXPRESSION OF NEURO ROPHICFAC ORS NGF BDNF AND RECEP ORS rkA, rkB AND rkC IN HE SPINAL CORD OF HE MONKEY W u X iaoqiong , L i Chang qi, L iu D an, Cai W eij un , L uo X ueg ang ( Department of Neurobiolo y, Xian Ya Medical Colle e, Central South University, Chan sha 410078) AbstractT o investi ate the expression of neurotrophic factor s and their receptors in th e spinal cord of adult monk ey, im muno- histoch emistry w ith antibodies a ain st neurotrophic factors nerve row th factor ( NGF ) , brain derived neurotr op hic factor ( BDNF) and the neurotrophic factor r eceptors, trkAtrkB and trkC w as used. NGF immu noreactive positive neurons w ere pr e- sent in all the laminae of rey m atter, lial cells in the rey and wh ite matter w ere positively stained for NGF. BDNF immunor e- , , active positive neurons w ere observed in different neurons of spinal cord especial in m otoneurons trkA trkB and trkC im- munoreactivity w as observed in neurons and lial cells of the rey matter. T he data su est th at neurotroph ins may play an im- portant role in maintain in th e physiolo ical fun ction of neurons in th e spinal cord . (Fi ures ah on plate 50) , ,