声像图表现与VEGFC表达与乳腺癌腋淋巴结转移关系分析.pdfVIP

· · 396 ChineseMedical of 2007，V01．24No．4 JournalMetallurgicalIndustry，August 声像图表现和VEGF—C表达与乳腺癌腋淋巴结转移关系分析 赵汉学 朱 强 肖 萍黄慧莲 首都医科大学附属北京同仁医院超声诊断科(北京100730) 摘要 目的：探讨乳腺癌原发灶声像图表现和VEGF—C表达情况与患者腋淋巴结转移的关系。方法：回顾性分析经手术和病理证实的67 例乳腺癌患者的原发灶声像图表现和VEGF—C表达情况与腋淋巴结状态的关系。结果：超声所示乳腺癌原发灶大小、边界、内部血流丰富程度等 表现与VEGF—C表迭情况结合分析有助于判断乳腺癌有无腋淋巴结转移。 关键词乳腺肿瘤；超声；内皮生长因子；肿瘤转移 中图分类号R737．9 文献标识码 A 文章编号 1005—5495(2007)04—0396—03 nodesmetastasesofbreastcancerultrasoundwithvascularendothelialfactorC．ZHA0Han—xue，ZHU Evaluatingaxillarylymph by growth Qiang， XIAO Medical 100730 Ping，eta1．DepartmentofDiagnosticUltrasound，BeijingTongrenHospital，CapitalUniversity，Beijing Abstract evaluate nodemetastasesofbreastcancerultrasoundwith breastcancer 0bjective：Toaxillarylymph by VEGF-C．Methods：67 confirmed wererecruitedinthis which nodularmetastaseswerefoundin35cases．Thesize， patients pathologically study，amongaxillarylymph andthe oftumorwererecorded．TheVEGFCwereutilizedinourimmunohistochemical tumoralsize， margin vascularity experiment．Results：The intumorswererelatedto nodularmetastases．The in cancerwith marginvascularity axillarylymph VEGF-C ratiosbreast expression axillarylymph nodemetastaseswere thanlesionswithoutmetastases．The were thecriteriaoflesion higher sensitivity，specificity90．9％，90％，respectively，using 二2em，ill—defined II andVEGF-C withVEGF—Ccanbevitalvaluefor margin，gradeandⅢflow positiveexpression．Conclusions：Ultrasound nodes