Biocompatible Bone Fillers.ppt

Biocompatible Bone Fillers Pelvic Osteolysis Felicia Shay Computer Integrated Surgery II Bone Filler Ingrowth Bibliography: Papers S. Takaaki, M. Saito, K. Kawagoe, et al. “New hydroxyapatite composite resin as a bioactive bone cement: improvement of handling and mechanical properties.” Bioceramics. Vol. 11 (1998): World Scientific Publishing Co. Pte. Ltd, 251-254. W. F. Mousa, M. Kobayashi, S. Shinzator, et al. “Biological and mechanical properties of commercial PMMA bone cements containing AW-GC filler” Bioceramics. Vol. 12 (1999): World Scientific Publishing Co. Pte. Ltd, 545-548. Y. Okada, K. Kawanabe, H. Fujita, et al. “Bonding behavior of bioactive bone cement in segmental replacement of rabbit tibia: comparison with PMMA bone cement.” Bioceramics. Vol. 12 (1999): World Scientific Publishing Co. Pte. Ltd, 529-533. Bibliography: Continued N. Asaoka, M. Misago, M. Hirano, et al. “Mechanical and chemical properties of the injectable calcium phosphate cement.” Bioceramics. Vol. 12 (1999): World Scientific Publishing Co. Pte. Ltd, 525-528. F.C.M. Dreissens, M.G. Boltong, E.A.P. de Maeyer, et al. “Comparative Study of Some Experiemental or Commercial Calcium Phosphate Bone Cements.” Bioceramics. Vol 11 (1998): World Scientific Publishing Co. Pte. Ltd, 231-234 Test Materials/Composition PMMA PMMA Composites Bioglass PMMA/ Ca/P Composites Ca/P Composites Hydroxyapatite Background Fundamental of: PMMA Ca/P Bioglass Uses Ideal Methods of Testing Cyclic Wear: Compression Tension: Figure 1 X-ray Diffraction: Analyze reaction Scanning Electron Microscope (SEM): Microstructure Injectability Setting time Comparison of Ca/P Materials Compressive Strength Bioactive vs PMMA: after time PMMA in Rat Tibia: 8 weeks Weaknesses Lack of: In vivo testing for some experiences Long term testing for analysis Testing of different porousity Uniform testing for all types of materials Dependency upon: Mixing P/L ratio dependent Strengths Uniform Testing methods In vivo like environments