痰热清注射液对急性脑梗死患者血中IL1β和ICAM1水平的影响.pdfVIP

中国中医急症2008年11月第17卷第1l期JETCM．Nov．2008．V01．17，No．1l ·临床研究· 痰热清注射液对急性脑梗死患者血中IL一1 13 及ICAM一1水平的影响 吴云虎 任 丁 黄建民 中图分类号：R743．9文献标识码：B文章编号：1004—745X(2008)1l一1509—02 【摘要】 目的观察痰热清注射液治疗急性脑梗死的临床疗效及其作用机制。方法将急性脑梗死患者65例 随机分为两组，治疗组35例予以痰热清注射液，对照组30例给予清开灵注射液，疗程14d；检测治疗前后血 清IL一1B及ICAM一1水平，同时进行神经功能评分比较。结果治疗组l临床疗效优于对照组；两组治疗后血 清IL—lB及ICAM—I水平较治疗前显著降低，而治疗组降低更明显。结论痰热清注射液治疗急性脑梗死安 全有效，其作用机制可能为降低了IL—lB及ICAM—l水平。 ICAM一1 【关键词】急性脑梗死 IL—lB 痰热清注射液 Effectofthe onIL—landICAM—lintheBloodofPatientswithAcuteCerebrM TanreqingInjection p Infarction WUYun—hu．REN Jian—min Ding,HUANG ChineseTraditional 530011) 舭AffiliatedRuikangHospitalofGuangxi College(Nanning the of inthetreatmentof with 【Abstract】 effectsandmechanism Objective：Tostudy TanreqingInjection patients acutecerebralinfarction．Methods：35Patientswithacutecerebralinfarctiontreated asa byTanreqingInjection treatmentand30ca$esofcontrol treated ofserumIL—landI— group group byQingkailingInjection．DetectionB CAM一1levels．andnervefunctionscorewere betweentwo of compared groups．Results：nedisappearance and and numberof after14dwere intwo havestatistical symptomssigns average days comparedgroups signifi— cance．ThelevelsofIL一1BandICAM—lintwo hadbeen reduced by groups significantly TanreqingInjection,and morereducedinthetreatmentthancontrol mechanismisthatthelevelsofIL—lBand group group．Conclusion：ne ICAM—lintheserumhadbeen reduced significatlybyTanreqingInjection． words】Ac