丙泊酚和传统麻醉剂用于成人胃肠镜检查效果比较的Meta分析.docVIP

丙泊酚与传统麻醉剂用于成人胃肠镜检查效果比较的Meta分析 Meta-analysis?of?the?use?of?propofol?as?a?sedative?agent?in?gastrointestinal?endoscopy收藏本页导出题录 作　　者：牛清?;张宗美?;陈树菊?Niu?Qing,?Zhang?Zongmei,?Chen?Shuju?（The?People＇s?Hospital?of?Dongying?City,?Shandong?Province,?Dongying?257000,?China）机构地区：山东省东营市人民医院,257091?出　　处：《中国实用护理杂志》 2014年第30卷第32期 48-54页,共7页《Chinese?Journal?of?Practical?Nursing》摘　　要：目的 应用Meta分析探讨与传统麻醉剂相比,丙泊酚用于胃肠镜检查的有效性和安全性.方法 参照Cochrane协作网制定的检索策略进行检索,在MEDLINE、Web of Science、万方和CNKI数据库中检索将丙泊酚和传统麻醉剂以随机对照试验用于胃肠镜检查的相关文献,评估其操作及恢复效果.结果 共计纳入21项病例对照研究,共1 765例研究对象,其中包括894例接受丙泊酚麻醉患者和871例接受传统麻醉剂麻醉患者.结果显示,与传统的麻醉剂相比较,丙泊酚对胃肠镜检查时间的影响无统计学意义;但可显著缩短手术恢复时间和平均出院时间;且恢复评分更高.在对种族进行亚组分析的结果中显示：丙泊酚可显著缩短亚洲人群胃肠镜检查手术时间,但对欧洲人群影响不大.对造影方法进行亚组分析结果显示：丙泊酚可显著缩短内镜下逆行胆胰管造影术（ERCP）中胃肠镜检查手术时间,但对上消化道内镜造影（UGE）和结肠镜检查（Colonscopy）影响不大.结论 丙泊酚用于胃肠镜检查恢复时间和出院时间短,麻醉后恢复评分高,说明丙泊酚用于胃肠镜检查安全有效.Objective?To?assess?the?efficacy?and?safety?of?propofol?sedation?for?gastrointestinal?endoscopy,we?conducted?a?Meta-analysis?of?randomized?controlled?trials?（RCT）?comparing?propofol?with?traditional?sedative?agents.Methods?Referring?Cochrane?Collaboration?search?strategy?to?develop?retrieval?in?Medline,Web?of?Science,Wanfang?and?CNKI?database?to?retrieve?the?anesthetic?propofol?and?traditional?agents?in?the?literature?for?randomized?controlled?trials?of?gastrointestinal?endoscopy,surgery?and?assess?their?recovery?effect.Results?Twenty-one?original?RCTs?investigating?a?total?of?1?765?patients,of?whom?894?received?propofol?only?and?871?received?traditional?sedative?agents?only,met?the?inclusion?criteria.Research?showed?that?compared?with?traditional?anesthetics,no?significant?differences?existed?in?anesthetic?effects?of?propofol?on?gastrointestinal?endoscopy?surgery?time.However,surgery?can?significantly?shorten?recovery?time?and?the?average?discharge?time;?and?higher?recovery?rates.The?result?of?racial?subgroup?analysis?showed：the?anesthetic?propofol?can?significantly?shorten?the?time?of?gastrointestinal?endoscopy?surgery?for?Asian?populations,but?ha