不同剂型蜂胶对正常小鼠和高血糖小鼠血糖的影响_周先汉.pdfVIP

DOI :10.13989/j.cnki .0517 -6611.2009.09.154 , Journal of Anhui Agri.Sci.2009, 37(9):4065-4066,4109　　　　　　　　　　　　　　　　　常俊香　　况玲玲 周先汉,张冰慧,魏 巍,余正家　(, 230009) 　用蜂胶醇提物、蜂胶胶囊和蜂胶脂质体灌胃高血糖小鼠和正常小鼠,观 3 种不同剂型蜂胶对正常小鼠血糖和高血糖小鼠体重、 血糖和抗氧化能力的影响。结果表明, 在蜂胶净含量相同的情况下, 蜂胶脂质体在降血糖、减缓高血糖小鼠消瘦症状和提高其抗氧化能 力的效果较好;而3种剂型蜂胶对正常小鼠的血糖均无明显影响。 　蜂胶;高血糖;脂质体;抗氧化能力 　TS 896.6　　　A　　　0517-6611(2009)09-04065-02 Effectsof Propolis with Different Dosage Formson Blood Glucose ofNormal and HyperglycemiaMice ZHOU ian-han et al　(Biological and Food Engineering College of Hefei Indu try Univer ity, Hefei, Anhui 230009) Abstract 　Normal and hyperglycemia mice received ga tric perfu ion treatment with ethanol extract of propoli , propoli cap ule and propoli lipo ome, then the effect of 3 different do age form of propoli on weight, blood gluco e and antioxidant capacity of normal and hyperglycemia mice were ob erved. The re ult howed that under the ame do age of propoli , propoli lipo ome had good effect on reducing blood gluco e, mitigate emaciation ymptom and improving antioxidant capacity of hyperglycemia mice, and the 3 do age form propoli had no obviou effect on blood gluco e of normal mice. Key words　Propoli ;Hyperglycemia;Lipo ome;Antioxidant capacity 　　 (100 mg/kg)()。、 , , , 100 g 1 ml [1-2] 。、、 。0.9 % [3] 、 。 100 g 1 ml 。ig ,28 d。 ,,、 1.2.3　、。 , , 16 h, 90 mg/kg, 。,, 7 ,12 h,,, , 11.0 mmol/L 。 。 5 , 10 , 1　 Group Ⅱ、Group Ⅲ(100 mg/kg)、 1.1　　 Group Ⅳ(333mg/kg)、Group Ⅴ(1.5 g/kg) 1.1.1　。ICR ,(20 ±2)g,(21 ± Group Ⅵ (2.5 g/kg)。3 , 1)℃。(60±5 )%(, (100 mg/kg)()。 )。 、 1.1.2　。:(Sigma ); , 100 g 1ml 。10 ();();( Group Ⅰ。、 );();(); 0.9%100 g 1 ml 。 (SOD)、(MDA)( ig ,28 d。 )。:Omnite t EZ; 1.3　 CA-0204-12-FNG;FJ-20