像素激光配合果酸治疗黄褐斑的临床疗效.docVIP

像素铒激光配合果酸治疗黄褐斑的疗效观察 刘梅，王娟，张杰，张元风 北京京城皮肤病医院，北京 100192； [摘要]目的：观察像素激光（2940）联合羟基乙酸（果酸）治疗黄褐斑的临床疗效和安全性，掌握像素激光和果酸换肤的治疗方法。方法：应用质量浓度20%，35%的果酸对30例黄褐斑患者进行治疗，2-3周一次，5次为1疗程。应用短脉宽像素激光对30例黄褐斑患者进行治疗，每2-3周一次，4次为一疗程，两种方法交替使用，15天治疗一次。有两名固定的医生对患者进行黄褐斑皮损面积和严重程度指数（MASI）的评分，采用自身治疗前后对照进行疗效观察并记录患者治疗后的反应。结果：随着治疗次数的增加，褐色斑逐渐变淡，MASI评分逐渐下降。30例患者完成一个疗程的治疗，有效率：表皮型黄褐斑83.33%，混合型44.44%，表皮型比混合型患者MASI下降更显著（P0.05），完成了一个疗程的30例患者中，有效率为60%，治疗过程中，30例患者做果酸治疗未发现灼痛，红斑等不良反应；做像素激光未发现色沉，瘢痕等不良反应。结论：像素激光联合果酸治疗黄褐斑，是一种安全性好，修复快，不良反应少的方法；对于表皮型黄褐斑比混合型效果更明显。 [关键词]:像素激光 果酸 黄褐斑 Pixel laser treatment of melasma with the efficacy of acid [Abstract] Objective: To observe the Pixel laser (2940) combined with glycolic acid (AHA) in the treatment of melasma clinical efficacy and safety, master pixel laser and chemical peel treatments. Methods: The concentration of 20%, 35% of the acid were 30 cases of chloasma treated 2-3 weeks time, 5 times for a course of treatment. Application of short pulse laser pixels were 30 cases of melasma treatment, once every 2-3 weeks, four times for one course, two methods are used interchangeably, 15 days of treatment time. There are two doctors on fixed lesions in patients with melasma area and severity index (MASI) score, for the use of self-efficacy before and after treatment were observed and recorded the response of patients after treatment. Results: The number of treatments increases, the brown spots gradually fades, MASI score decreased. 30 patients completed a course of treatment, efficiency: 83.33% of epidermal-type melasma, mixed 44.44%, than the mixed type skin decreased more significantly MASI patients (P 0.05), completed a course of 30 patients , the effective rate of 60% during the treatment, acid treatment of 30 patients do not find burning, redness and other side effects; did not find the color pixel laser Shen, scars and other adverse reactions. Conclusion: Pixel laser and acid treatment of melasma, is a safe and good, quick repair, adverse reaction method; for epidermal melasma