疏血通对急性脑梗死40例患者血PL选择素表达及炎症的影响.pdfVIP

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疏血通对急性脑梗死40例患者血PL选择素表达及炎症的影响.pdf

疏血通对急性脑梗死40例患者血PL选择素表达及炎症的影响.pdf

世界中医药2010年1月第5卷第1期 疏血通对急性脑梗死40例患者血P一、L一选择素 表达及炎症的影响 周义杰 王 红 李志英 韦华军 王培力 (桂林市中医医院,桂林市l艋桂路2号,541002) 摘要 目的:观察疏血通注射液对脑梗死患者P一、L一选择素表达及对炎症反应的影响,研究其干预脑缺血后炎症反应的环节 及作用机制。方法:将诊断明确的急性脑梗死住院患者80例随机分为2组,治疗组40例,对照组40例。对照组给予西医常规 治疗:抗血小板聚集、控制脑水肿、改善脑血循环、改善脑细胞代谢、防治并发症及支持疗法;治疗组在对照组的基础上加用 梗死患者有较好的疗效,其作用机制与干预急性脑梗死患者P一、L一选择素的表达,调节炎症反应有关。 关键词 急性脑梗死/中医药疗法;@疏血通注射液 of onP-SelectinandL-Selectin andInflammationon40PatientswithAcuteCerebralInfarc- ImpactShuxuetong Expression tion Zhou Yijie,WangHong,LiZhiying (Guilin TraditionalChinese Province,Postcode:541002) Hospitalof Medicine,Add.:No.2,LinguiRoad,Guilin,Guangxi Abstract observethe of onthe of C—reactive inthe P—selectin,L—selectin,and Objective:To impactShuxuetongexpression protein cerebral the mechanism wererandomizedtore— conditionofacute infarction,andstudyintervention thereof.Methods:Eightypatients ceive with250ml0.9%Sodium routine Shuxuetong(6ml,diluted Chloride,onceperday)plustreatments(anti—plateletaggregation, 14consecutive those theroutinetreatments clinical etc.)for days,controlledby receiving only(anti-plateletaggregation,etc.).The CRPwere effective effectiverate the effect,P.,L.selectin,andobserved.Results:Thesignificantrate(72.5%)andof(92.5%)of treatmentwere thanthoseofthecontrol treatment,both inall grouphigher group(50%,75%,P0.05).Aftergroupsimproved abovementioned thetreatment parameters(P0.05),withgroupbeingsignificantly intervening the ofP

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