408例70岁以上老年肺癌患者的预后因素分析（英文）.pdfVIP

Chinese-German Journal of Clinical Oncology December 2012, Vol. 11, No. 12, P699–P704 DOI 10.1007/s10330-012-1016-7 Prognostic factors in 408 elderly lung cancer patients over 70 years old 1 2 1 2 1 1 Hua Zheng , Li Tong , Ying Hu , Weihua Wu , Hongmei Zhang , Baolan Li 1 General Department, Beijing Chest Hospital of Capital Medical University, Beijing 101149, China 2 Department of Oncology, Beijing Chest Hospital of Capital Medical University, Beijing 101149, China Received: 10 May 2012 / Revised: 16 May 2012 / Accepted: 25 July 2012 © Huazhong University of Science and Technology and Springer-Verlag Berlin Heidelberg 2012 Abstract Objective: The incidence and mortality of lung cancer in people over 70 years were increased in the past 10 years. We defined age 70 years as boundary line of the elderly patients in lung cancer and analyzed and identified the fac- tors affecting prognosis. Methods: A retrospective study had enrolled 408 cases of lung cancer aged over 70 years old and SPSS13.0 software was used in univariate analysis and COX regression analysis to analyze factors affecting prognosis, such as gender, age, complications, symptoms, pathological type, clinical stage, effusion, surgery, radiotherapy, chemotherapy and so on. Results: In univariate analysis, symptoms, stage, effusion, surgery, chemotherapy and chemotherapy cycles showed affecting prognosis significantly. In COX regression analysis, it showed that clinical stage (P = 0.000), surgery (P = 0.013), chemotherapy cycles (P = 0.001) were independent prognostic factors. Conclusion: Elderly lung cancer patients could be benefit from surgery and