中重度缺血性二尖瓣反流患者行二尖瓣置换同期冠状动脉旁路移植术的临床研究.pdfVIP

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中重度缺血性二尖瓣反流患者行二尖瓣置换同期冠状动脉旁路移植术的临床研究.pdf

安 徽 医 药 Anhui Medical andPharmaceutical Journal 2015 Mar;19(3) ·471 · ◇临床医学◇ 中重度缺血性二尖瓣反流患者行二尖瓣置换 同期冠状动脉旁路移植术的临床研究 郭志祥,张成鑫,汪 欢,葛圣林 (安徽医科大学第一附属医院,安徽 合肥 230022) 摘要:目的 探讨二尖瓣置换(mitral valve replacement,MVR)同期冠状动脉旁路移植术(coronary artery bypass grafting,CABG) 治疗中重度缺血性二尖瓣反流 (ischemic mitral regurgitation,IMR)的效果。方法 2010 年7 月—2013 年1 月,16 例冠状动脉 粥样硬化性心脏病(coronary artery disease,CAD)合并中重度IMR 的患者接受了CABG联合 MVR术。其中男性8 例,女性8 例;平均年龄(63.4±7.6)岁。术前经胸超声心动图示中度二尖瓣反流2例,中重度8例,重度6 例。比较患者术前及术后经 胸超声心动图资料。结果 院内死亡1 例。术后复查超声心动图示二尖瓣无反流10例,轻度反流5 例,轻中度反流1 例。左 心室舒张末内径(leftventricularenddiastolic diameter,LVEDD)从(60±13)mm下降到术后12个月随访时的(47 ±12)mm(P< 0.05)。结论 二尖瓣置换同期冠状动脉旁路移植术治疗中重度缺血性二尖瓣反流的近期效果满意,并能明显改善左心室功 能。 关键词:二尖瓣反流;冠状动脉旁路移植术;心肌缺血 doi:10.3969/j.issn.1009 -6469.2015.03.018 A clinical research ofmitral valve replacement combined with coronary artery bypass graft surgery in patients with moderatetosevere ischemic mitral regurgitation GUO Zhixiang,ZHANG Chenxin,WANG Huan,et al (The FirstAffiliatedHospital ofAnhui Medical University,Hefei,Anhui 230022,China) Abstract:Objective To investigate the impact of combined coronary artery bypass grafting (CABG)and mitral valve replacement (MVR)in patientswith moderatetosevere ischemic mitral regurgitation (IMR).Methods From July 2010 to January 2013,16 pa tients ofcoronary artery disease with moderatetosevere IMRunderwent mitral valve replacement combinedwith coronary artery bypass graft surgery.There were 8 male and 8 female patients,with a mean age of (63.4 ±7.6)years.Preoperative transthoracic echocardio graphy showedmoderateIMRin2 cases,moderateto severein8 casesandseverein6 cases.Thedataofpreoperativetransthoracic ech ocardiography were compared with postoperative ones.Results Hospital mortality was 6.25%(1 case).Postoperat

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