卵巢成熟性畸胎瘤伴甲状腺肿类癌1例及文献复习.pdfVIP

泸州医学院学报 2015年 第38卷 第2期 Journal ofLuzhou MedicalCollege Vol.38 No.2 2015 139 论著 卵巢成熟性畸胎瘤伴甲状腺肿类癌1例及文献复习* 夏 天袁肖秀丽袁周铁军袁罗 华 渊泸州医学院附属医院病理学科袁四川泸州646000冤 摘 要 目的:探讨 1例卵巢成熟性畸胎瘤伴甲状腺肿类癌的临床病理特征遥 方法:对1例诊断为卵巢成熟性畸胎瘤伴甲状 腺肿类癌患者的临床资料尧组织学形态及免疫组化结果进行分析袁并对相关文献进行复习遥 结果:本例为卵巢成熟性畸胎瘤伴甲 状腺肿类癌袁病理学检查除成熟性畸胎瘤成分外袁另见由甲状腺和类癌组织混合成的结节一枚袁类癌细胞较小且大小相仿袁染色 质均匀袁核分裂少见袁免疫组化院甲状腺滤泡上皮细胞TG(+)尧TTF-1(+)袁类癌细胞CD99(+)尧CgA(+)尧Syn(+)尧CK7(-)遥结论:卵巢 成熟性畸胎瘤伴甲状腺肿类癌为罕见的病变袁临床患者多无典型症状袁且类癌成分多与甲状腺组织混杂于畸胎瘤中袁容易漏诊袁 故应广泛取材并提高对卵巢成熟性畸胎瘤伴甲状腺肿类癌组织学特征及免疫表型的认识袁对累积资料袁避免临床误诊尧漏诊具 有重要的价值遥 关键词 卵巢甲状腺肿类癌曰畸胎瘤曰病理特征 中图分类号 R361+.2曰R365 文献标志码 A doi:10.3969/j.issn.1000-2669.2015.02.006 Ovarianmature cysticteratoma accompaniedwithstrumal carcinoid: acase reportandliterature review XiaTian, Xiao Xiuli,ZhouTiejun, Luo Hua Department ofPathology, theAffiliated Hospital ofLuzhou Medical College Abstract Objective: To discuss the clinicopathologic features of ovarian mature cystic teratoma with strumal carcinoid. Methods: Clinical data袁pathological diagnosis and immunohistochemical results of a case of ovarian mature cystic teratoma with strumal carcinoid were analyzed袁and related literatures were reviewed. Results: This case was an ovarian mature cystic teratoma, histopathological examination revealed a nodule of strumal carcinoid. It mainly consisted of unequal-sized thyriod follicle and carcinoid cells. Thyriod follicle epithelial cellswere positivefor TG andTTF-1 and carcinoid cellswere positivefor CD99, CgA, Syn,but nagtive for CK7. Conclusions:Ovarian mature cystic teratoma with strumal carcinoid is a rare disease. It usually lack of typical clinical symptom and carcinoid cells always mix with thyriod tissue. It is easilly misdiagnos