PVP术后再骨折风险研究文献阅读.pptVIP

Percutaneous vertebroplasty (PVP) is an efficient procedure to treat pain due to osteoporotic vertebral compression fractures (OVCFs). However,some patient populations experience recurrent vertebral fracture after initial successful procedure. There are a lot of literatures about the effectiveness of this procedure but few concerning the development of recurrent, new compression fracture. Background The purpose of our study was to investigate the factors affecting new compression fractures in vertebral bodies adjacent to or remote from those previously treated with PVP. Objective Between September 1999 to December 2001, we performed percutaneous vertebroplasty in 311 consecutive patients with symptomatic OVCFs. Overall follow-up data in the remaining 244 individuals (78%) were available for this study. The overall numbers of the treated vertebrae were 382 levels. There were 37 male and 207 female patients (mean age 66.4 years) and the mean follow up duration was 52.5 months (range 38–67 months). Materials and methods A GROUP : Those patients who developed new, acute/subacute symptomatic OVCFs during the follow up period were grouped into ‘‘new symptomatic compression fracture’’. B GROUP : The others, who did not experience further symptomatic OVCFs were considered as control group. Materials and methods parameters: age, gender, the date initial vertebroplasty was performed, vertebral level(s) and the number of vertebra treated, anterior-to-posterior body height ratio of the fractured vertebra，amount of PMMA injected per vertebral body, existence of intradiscal PMMA leakage, date and vertebral level(s) at which subsequent vertebral body fractures were diagnosed. A-P rate Materials and methods Diagnosis of new vertebral compression fracture 1：plain radiography showed a definite decrease in the height of the vertebral b