术后认知功能障碍和阿尔茨海默病相关的发病机制思考.pdfVIP

( ) 2011 2 32 2 423 * 胡中华 欧阳文 : 术后认知功能障碍是手术麻醉后的并发症之一, 阿尔茨海默病是一种 见的慢性进行性神经退行性疾病, 在发病机 制方面二者存在诸多的相似点, 且目前在此方面对二者的研究都没有取得重大进展, 有必要从发病机制角度对二者进行 相关的辩证思考, 以便更好地指导临床及基础研究 : 认知, 阿尔茨海默病, 辩证思考 : R74 1 : A : 1002- 0772( 2011) 02- 0069- 03 Postoperative Cognitive Dysfunction and Alzheimer s Disease from Pathogenesis H U Zhong-hua, O U YA N G Wen. The T hird X iangy a H osp ital of Center outh University , Changsha 4 10013, China Abstract:P ostoperat ive cog nitiv e dys unct ion ( PO CD ) is one o co mplicatio ns a ter sur ger y and anesthesia. A lzheimer s disease( A D) is an insidiou s and pro gr essive neuro deg ener ative disor der o the elder ly. Since the similarit ies betw een PO CD and A D o n pathog enesis, and the r esear ch hav e no br eakthr ough . It is necessar y to have the dialectical thinking o PO CD and A D r om pathogenesis, w hich w ill be better o r our clinical and basic r esear ch . Key Words:cog nitio n, A lzheimer s disease, dialectical thinking 1 , , PO CD ( posto perat ive cog nitive dys unctio n, , PO CD) , PO CD , , , - 1- 6 , , , , , , , , , [ 1- 4] , : , , 1. 1 1. 3 , ,