先天性心脏病_风湿性心脏病及冠状_省略_桥术患者围手术期心肌酶变化的比较_陈长春.pdfVIP

·600 · 2003 8 41 8 　Chin J Su g, August 2003, Vol.4 1,No.8 ·· 、 陈长春　沈宗林　姬尚义　刘志红　胡应龙 　　【】　　 107 (CHD , 53 )、(RHD , 40 )(CAD , 14 ), 。 　　1 d, 1、3、5、8 d , (AST)、(CK, CK-MB)、1(LDH, LDH-1) 。 　　3 5 , 1 d 2 ～15 (P 0.05);3 d , 8 d RHD CAD LDH LDH-1 , 。(CCT) 。3 CCT 60 min , 3 CCT (P0.05);1 d CK-MB、CK AST CHD (P0.05);3 3、5、8 d 3 ;LDH LDH-1 1 ～ 8 d RHD (P 0.05)。 　CHD、RHD CAD 。 。CCT 60 min , 1 d CK-MB、CK AST CHD ;1～8 d LDH LDH-1 RHD 。CCT , 。 LDH LDH-1 。 【】　, ;　;　;　;　 Comparison of perioperative myocardial enzyme changes among congenital, rheumatic and coronary artery diseases　CHEN Chang -chun, SHEN Zong-lin, JI Shang-y i, LIU Zhi-hong, HU Ying-long .TheDepartment of Cardiac Surgery , Sun Yat en Cardiova cular Ho pital, Shenzhen 518020, China 【Abstract】　Objective 　To obse ve and compa e pe iope ative myoca dial enzyme changes in 107 patients with congenital (CHD, n =53), heumatic (RHD, n=40)and co ona y a te y (CAD, n=14 )diseases, and to find whethe diffe ent diseases can affect the elease and ecove y of myoca dial enzymes afte hea t ope ations.　 Methods　On the day befo e ope ation and the 1st, 3 d, 5th and the 8th day afte ope ation, the venous blood was taken to measu e the elease of myoca dial enzymes:aspa tate aminot ansfe ase(AST), c eatine kinase (CK), MB isoenzyme of c eatine kinase (CK-MB), lactate dehyd ogenase (LDH )and LDH-1.　Results 　All the enzymes measu ed befo e ope ation in th ee g oups we e in the no mal ange;thei elease inc eased ab uptly on the 1st day postope atively to 2-15 times of those befo e ope ation;on the 3 d day, they ecove ed to some deg ees, and on the 8th day they ecove ed to no mal in all g oups except LDH and LDH-1 in h and CAD g oups. Because the ao tic c oss-clamp time (CCT)had a good positive co elation to the elease of myoca dial enzymes, those patients whose